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Ophthalmology · Conjunctiva and cornea: Terrien against Mooren
Sample itemA 55-year-old man has painless, slowly progressive thinning of the superior peripheral cornea with a yellow lipid line at the leading edge, a clear zone next to the limbus and no inflammation. The thinning is gutter-like with an intact epithelium. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Terrien marginal degeneration
Terrien marginal degeneration is a non-inflammatory, painless, slowly progressive peripheral thinning, usually superior, with lipid deposition and an intact epithelium. Mooren ulcer is painful, with an overhanging edge and inflammation. Treatment of Terrien is optical or surgical for astigmatism and perforation risk.
Option by option
A. Marginal catarrhal ulcer
Catarrhal ulcer lies near the limbus with a clear zone but is a red, irritated eye with an epithelial defect.
B. Peripheral ulcerative keratitis of rheumatoid arthritis
Peripheral ulcerative keratitis occurs with active systemic vasculitis and is painful and inflamed.
C. Terrien marginal degeneration (correct)
Correct. A painless, quiet, gutter-like peripheral thinning with a lipid edge is Terrien.
D. Mooren ulcer
Mooren ulcer is intensely painful, inflamed and has an overhanging undermined edge.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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