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Ophthalmology · Glaucoma: ghost cell glaucoma
Sample itemFour weeks after a dense vitreous haemorrhage, a patient who has had cataract surgery develops high intraocular pressure. The anterior chamber shows khaki-coloured cells with an open angle. What is the cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Degenerated red cells blocking the trabecular meshwork
Ghost cell glaucoma follows vitreous haemorrhage when degenerated, rigid khaki-coloured red cells reach the anterior chamber, through a disrupted anterior hyaloid, and clog the meshwork. The angle is open. Treatment is medical, with washout or vitrectomy if it persists.
Option by option
A. Pupillary block by posterior synechiae
Posterior synechiae produce iris bombe with a closed angle after uveitis.
B. Neovascularisation of the angle
Neovascular glaucoma follows ischaemic retinopathy and shows new vessels, not khaki cells.
C. Corticosteroid effect on the meshwork
Steroid glaucoma needs a steroid exposure and does not give khaki-coloured cells.
D. Degenerated red cells blocking the trabecular meshwork (correct)
Correct. Rigid ghost cells block the meshwork and the angle remains open.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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