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Ophthalmology · Retina: Hollenhorst plaque
Sample itemA 66-year-old smoker has had a brief episode of curtain-like vision loss in one eye. Fundus shows a bright, refractile yellow plaque at a retinal arteriolar bifurcation. Which source should be investigated?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Ipsilateral carotid artery atheroma
Hollenhorst plaques are cholesterol emboli, most often from an ipsilateral carotid atheromatous plaque, and signal stroke risk. Carotid Doppler imaging is the next step. Cardiac sources usually give fibrin-platelet or calcific emboli instead.
Option by option
A. Retinal vasculitis
Vasculitis gives sheathing and ischaemia, not refractile plaques.
B. Optic nerve glioma
Optic nerve glioma is a childhood tumour and does not embolise.
C. Left atrial myxoma
Atrial myxoma may embolise but gives tumour or fibrin emboli, not refractile cholesterol plaques.
D. Ipsilateral carotid artery atheroma (correct)
Correct. Cholesterol emboli point to carotid atheroma and need duplex scanning.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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