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Psychiatry · Substance use: ketamine misuse
Sample itemA 24-year-old who frequently uses ketamine at parties for months has urinary frequency, urgency and suprapubic pain with blood in the urine. Cultures are sterile. What is the cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Ketamine-induced cystitis
Chronic ketamine use damages the bladder, causing a contracted painful bladder, haematuria and sometimes hydronephrosis, with sterile urine. Stopping the drug is the first step in management.
Option by option
A. Bladder carcinoma
Bladder carcinoma is rare at this age and is not the usual result of ketamine use.
B. Ketamine-induced cystitis (correct)
Correct. Chronic ketamine use causes sterile inflammatory cystitis.
C. Schistosomal cystitis
Schistosomal cystitis follows exposure to freshwater in endemic areas.
D. Urinary tuberculosis
Urinary tuberculosis causes sterile pyuria but is not linked to ketamine use.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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