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Psychiatry · Organic mental disorders: subcortical vascular dementia
Sample itemA 68-year-old man with long-standing poorly controlled hypertension has slow thinking, apathy, shuffling gait and urinary urgency over three years. MRI shows extensive periventricular white matter change and lacunes, with preserved hippocampi. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Subcortical ischaemic vascular dementia
Small-vessel disease from hypertension causes subcortical ischaemic vascular dementia, with psychomotor slowing, executive dysfunction, gait disturbance and early urinary symptoms. Alzheimer disease causes early hippocampal memory loss, and Creutzfeldt-Jakob disease is rapidly progressive.
Option by option
A. Frontotemporal dementia
Frontotemporal dementia begins with personality change or language loss and focal frontotemporal atrophy.
B. Alzheimer disease
Alzheimer disease begins with episodic memory loss and hippocampal atrophy.
C. Creutzfeldt-Jakob disease
Creutzfeldt-Jakob disease progresses over weeks to months with myoclonus.
D. Subcortical ischaemic vascular dementia (correct)
Correct. White matter change, lacunes and a slow subcortical picture fit.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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