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Anatomy · Neuroanatomy
Sample itemA man has sudden severe back pain with saddle anaesthesia, early urinary retention, symmetrical bilateral leg weakness with brisk reflexes and prominent upper motor neurone signs. Which lesion is most likely?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Conus medullaris lesion
The conus medullaris ends at L1 to L2, and its lesions cause early bladder and bowel dysfunction, symmetrical saddle loss and a mix of upper and lower motor signs. Cauda equina lesions are asymmetrical, root-like and entirely lower motor.
Option by option
A. Femoral nerve palsy
Femoral nerve palsy affects thigh flexion and the knee jerk on one side only.
B. Lumbar root avulsion
Root avulsion is unilateral and lower motor in type.
C. Conus medullaris lesion (correct)
Correct. The conus lesion gives symmetrical early sphincter loss with mixed motor signs.
D. Peripheral neuropathy
Peripheral neuropathy is length dependent and does not cause saddle loss.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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