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ENT · Larynx and airway: myxoedema of the vocal folds
Sample itemA middle-aged woman has a gradually deepening hoarse voice, fatigue, constipation and cold intolerance. Laryngoscopy shows diffuse oedematous vocal folds. What is the most appropriate treatment of the voice change?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Thyroid hormone replacement
Hypothyroidism causes mucopolysaccharide deposition and oedema in the vocal folds, giving a low hoarse voice that improves with levothyroxine. Surgery is not needed.
Option by option
A. Voice rest alone
Voice rest does not correct the underlying cause.
B. Antireflux surgery
Antireflux surgery treats reflux laryngitis and not myxoedema.
C. Microsurgical stripping of the folds
Stripping treats Reinke oedema from smoking and is not the aim here.
D. Thyroid hormone replacement (correct)
Correct. Treating the hypothyroidism reverses the oedema and voice change.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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