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Psychiatry · Organic mental disorders: akinetic mutism
Sample itemAfter an anterior cerebral artery infarct, a 60-year-old man lies with eyes open, tracks the examiner with his gaze, but does not speak or move spontaneously. He responds with a few words when strongly stimulated. Vertical eye movements are normal. Which diagnosis fits best?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Akinetic mutism
Akinetic mutism results from bilateral medial frontal or anterior cingulate damage, leaving the patient awake and apparently attentive but without drive to speak or move. Locked-in patients have pontine damage with preserved awareness and cognition but cannot move except for vertical eye movements and blinking.
Option by option
A. Akinetic mutism (correct)
Correct. A lack of spontaneous speech and movement with preserved tracking after an anterior cerebral lesion is akinetic mutism.
B. Catatonic stupor
Catatonic stupor occurs in psychiatric or medical illness with signs such as posturing and negativism, and the lesion here is structural.
C. Locked-in syndrome
Locked-in syndrome results from a pontine lesion with quadriplegia and communication by vertical eye movements.
D. Persistent vegetative state
A vegetative state has sleep-wake cycles without awareness, and tracking is absent.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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