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Orthopaedics · Bone infection
Sample itemA man has a chronically discharging sinus over the tibia after an old open fracture. A radiograph shows a dense bone fragment lying in a lucent cavity with surrounding thick new bone. Which element must be removed to achieve cure?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Sequestrum
In chronic osteomyelitis, a sequestrum is a piece of dead bone separated from living bone, and bacteria hide on its avascular surface protected from antibiotics and host defences. The involucrum is the new bone surrounding it, and the cloaca is the opening through which pus drains.
Option by option
A. Involucrum
The involucrum is living new bone that gives stability and is retained where possible.
B. Sequestrum (correct)
Dead bone harbours bacteria beyond the reach of antibiotics, so sequestrectomy is needed.
C. Cloaca
The cloaca is only the drainage opening and will close once the infected dead bone is removed.
D. Periosteal new bone
Periosteal new bone is living reactive bone and is not the source of persistent infection.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.