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Ophthalmology · Ocular tumours
Sample itemAn elderly man has a pigmented eyelid margin lesion that has enlarged, has an irregular border, varied colour and episodic bleeding. What is the best next step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Biopsy with histological examination
Change in size, border, colour or bleeding suggests malignancy, such as melanoma or sebaceous carcinoma. Tissue diagnosis guides excision margins. Destroying the lesion without histology risks missing the diagnosis.
Option by option
A. Observe for six months
Delay risks progression of a possible malignancy.
B. Cryotherapy without tissue diagnosis
Ablation without histology loses diagnostic information.
C. Topical corticosteroid
Steroids do not treat pigmented tumours.
D. Biopsy with histological examination (correct)
Correct. Histology is needed to confirm or exclude malignancy.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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