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Psychiatry · Mood disorders: curriculum recognition
Sample itemA patient abruptly stops paroxetine and within two days has dizziness, electric-shock sensations, nausea, irritability and flu-like symptoms. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Antidepressant discontinuation syndrome
Abrupt stopping of a short half-life serotonergic drug causes self-limited symptoms within days. Serotonin syndrome occurs from excess serotonergic stimulation with clonus and hyperthermia.
Option by option
A. Antidepressant discontinuation syndrome (correct)
Correct. Rapid onset after stopping a short half-life drug is typical.
B. Relapse of depression
Relapse develops over weeks with mood symptoms.
C. Serotonin syndrome
Serotonin syndrome follows excess, not withdrawal.
D. Neuroleptic malignant syndrome
Neuroleptic malignant syndrome follows dopamine blockers.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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