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Anatomy · Embryology
Sample itemFrom which embryonic structure does the anterior pituitary (adenohypophysis) develop?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Rathke's pouch (oral ectoderm)
The adenohypophysis develops from Rathke's pouch, an upgrowth of oral ectoderm. The neurohypophysis develops from a downgrowth of neuroectoderm (the infundibulum). A persistent remnant of Rathke's pouch can give a craniopharyngioma.
Option by option
A. Rathke's pouch (oral ectoderm) (correct)
Correct. The anterior pituitary is of oral ectoderm origin.
B. Infundibulum (neuroectoderm)
The infundibulum forms the posterior pituitary and the stalk, which are neural in origin.
C. Third pharyngeal pouch
The third pharyngeal pouch gives the thymus and the inferior parathyroids.
D. Notochord
The notochord induces the neural plate and forms the nucleus pulposus, not the pituitary.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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