Try it
General Medicine · Cardiology: contraindications to thrombolysis
Sample itemWhich of the following is an absolute contraindication to thrombolysis in STEMI?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Previous intracranial haemorrhage
Absolute contraindications include prior intracranial haemorrhage, ischaemic stroke within 3 months, intracranial neoplasm or vascular malformation, active bleeding and suspected aortic dissection. Age and menstruation are not absolute barriers. Primary PCI is preferred when it is available in time.
Option by option
A. Age above 75 years
Old age raises risk but is not an absolute contraindication.
B. Controlled hypertension on treatment
Controlled hypertension is acceptable; severe uncontrolled hypertension is a relative one.
C. Previous intracranial haemorrhage (correct)
Correct. Prior intracranial haemorrhage carries a high risk of recurrence with lytics.
D. Menstruation
Menses is not a contraindication.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More General Medicine questions
- EndocrinologyA 19-year-old with type 1 diabetes presents with vomiting, deep rapid breathing, fruity…
- ElectrolytesWhich is the earliest ECG change in hyperkalaemia?
- Infectious diseaseWhat is the drug of choice for Pneumocystis jirovecii pneumonia in a patient with advanc…
- NeurologyA chronic alcohol user is brought in confused, with nystagmus and an unsteady gait. What…