Gastroenterology: ulcerative colitis features: practice question

A General Medicine question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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General Medicine · Gastroenterology: ulcerative colitis features

Sample item

A young man has bloody diarrhoea. Colonoscopy shows continuous mucosal inflammation from the rectum to the splenic flexure. Which extraintestinal association is characteristic?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Primary sclerosing cholangitis

Ulcerative colitis begins in the rectum and spreads proximally in a continuous fashion with mucosal involvement. Primary sclerosing cholangitis is a recognised association, especially in extensive disease. Perianal fistulae and ileal gallstones belong to Crohn disease.

Option by option

  • A. Primary biliary cholangitis

    PBC is not related to UC.

  • B. Gallstones from ileal disease

    Ileal gallstones occur in Crohn ileal disease.

  • C. Perianal fistula

    Perianal fistula suggests Crohn disease.

  • D. Primary sclerosing cholangitis (correct)

    Correct. PSC is a classic UC association.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this General Medicine question

What is the answer to this General Medicine question?

The best answer is D, Primary sclerosing cholangitis. Ulcerative colitis begins in the rectum and spreads proximally in a continuous fashion with mucosal involvement.

Why is "Primary biliary cholangitis" not the answer?

PBC is not related to UC.

Why is "Gallstones from ileal disease" not the answer?

Ileal gallstones occur in Crohn ileal disease.

Why is "Perianal fistula" not the answer?

Perianal fistula suggests Crohn disease.

What concept does this question test?

It tests Gastroenterology: ulcerative colitis features in General Medicine. Primary sclerosing cholangitis is a recognised association, especially in extensive disease. Perianal fistulae and ileal gallstones belong to Crohn disease.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gastroenterology: ulcerative colitis features?

For each disease know the classic presentation, the best test, and the first-line treatment. Then use the flashcards and the other General Medicine questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.