Systemic paediatrics: cystic fibrosis lung disease: practice question

A Pediatrics question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pediatrics · Systemic paediatrics: cystic fibrosis lung disease

Sample item

A 12-year-old with cystic fibrosis has repeated exacerbations and sputum culture growing mucoid Pseudomonas aeruginosa. Which therapy is recommended for chronic suppression?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Inhaled tobramycin

Pseudomonas aeruginosa colonisation drives lung decline in cystic fibrosis. Inhaled antibiotics such as tobramycin or aztreonam suppress infection, along with airway clearance and CFTR modulators.

Option by option

  • A. Inhaled tobramycin (correct)

    Correct. Inhaled tobramycin suppresses Pseudomonas.

  • B. Inhaled cromolyn

    Cromolyn has no role.

  • C. Intravenous steroids

    Steroids do not treat the infection.

  • D. Oral amoxicillin

    Oral amoxicillin has no activity against Pseudomonas.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Pediatrics question

What is the answer to this Pediatrics question?

The best answer is A, Inhaled tobramycin. Pseudomonas aeruginosa colonisation drives lung decline in cystic fibrosis.

Why is "Inhaled cromolyn" not the answer?

Cromolyn has no role.

Why is "Intravenous steroids" not the answer?

Steroids do not treat the infection.

Why is "Oral amoxicillin" not the answer?

Oral amoxicillin has no activity against Pseudomonas.

What concept does this question test?

It tests Systemic paediatrics: cystic fibrosis lung disease in Pediatrics. Inhaled antibiotics such as tobramycin or aztreonam suppress infection, along with airway clearance and CFTR modulators.

How hard is this question?

We tag it as a multi-step question: it asks you to combine more than one idea. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Systemic paediatrics: cystic fibrosis lung disease?

Memorise milestones and the vaccine schedule as tables and revise them often. Then use the flashcards and the other Pediatrics questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.