Tumor suppressors: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Tumor suppressors

Sample item

APC mutation is strongly linked to what cancer pathway?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

B. Colorectal carcinoma

This item reviews Tumor suppressors; Colorectal carcinoma is the best answer because it directly fits the mechanism or morphology described.

Option by option

  • A. Osteosarcoma

    Osteosarcoma is not supported by the stated finding.

  • B. Colorectal carcinoma (correct)

    Correct. Colorectal carcinoma is supported by the defining finding.

  • C. Melanoma only

    Melanoma only does not match the key mechanism or pattern.

  • D. Lung cancer only

    Lung cancer only is plausible but is not the best fit here.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is B, Colorectal carcinoma. This item reviews Tumor suppressors; Colorectal carcinoma is the best answer because it directly fits the mechanism or morphology described.

Why is "Osteosarcoma" not the answer?

Osteosarcoma is not supported by the stated finding.

Why is "Melanoma only" not the answer?

Melanoma only does not match the key mechanism or pattern.

Why is "Lung cancer only" not the answer?

Lung cancer only is plausible but is not the best fit here.

What concept does this question test?

It tests Tumor suppressors in Pathology. The correct option holds because: Correct. Colorectal carcinoma is supported by the defining finding.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Tumor suppressors?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.