Leukemia: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Leukemia

Sample item

Which chromosome abnormality is classic for CML?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

A. Philadelphia chromosome

This item reviews Leukemia; Philadelphia chromosome is the best answer because it directly fits the mechanism or morphology described.

Option by option

  • A. Philadelphia chromosome (correct)

    Correct. Philadelphia chromosome is supported by the defining finding.

  • B. Turner karyotype

    Turner karyotype is plausible but is not the best fit here.

  • C. X monosomy

    X monosomy is not supported by the stated finding.

  • D. Trisomy 21 only

    Trisomy 21 only does not match the key mechanism or pattern.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is A, Philadelphia chromosome. This item reviews Leukemia; Philadelphia chromosome is the best answer because it directly fits the mechanism or morphology described.

Why is "Turner karyotype" not the answer?

Turner karyotype is plausible but is not the best fit here.

Why is "X monosomy" not the answer?

X monosomy is not supported by the stated finding.

Why is "Trisomy 21 only" not the answer?

Trisomy 21 only does not match the key mechanism or pattern.

What concept does this question test?

It tests Leukemia in Pathology. The correct option holds because: Correct. Philadelphia chromosome is supported by the defining finding.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Leukemia?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.