Try it
Dermatology · Papulosquamous disorders: Grover disease
Sample itemAn elderly man confined to bed in a hot ward develops a sudden, itchy eruption of discrete red papules on the chest and back. Histology shows focal acantholysis. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Transient acantholytic dermatosis (Grover disease)
Grover disease is a transient acantholytic dermatosis of the trunk in middle-aged and older men, provoked by heat, sweating and bed rest. Treatment is cooling, emollients and topical steroids. It differs from pemphigus by lacking mucosal disease and persistent blisters.
Option by option
A. Pemphigus vulgaris
Pemphigus vulgaris causes flaccid bullae with mucosal erosions.
B. Transient acantholytic dermatosis (Grover disease) (correct)
Correct. Heat-provoked truncal papules with focal acantholysis are typical of Grover disease.
C. Scabies
Scabies would show burrows and involve finger webs and genitals.
D. Pityriasis rosea
Pityriasis rosea follows a herald patch with a Christmas tree pattern.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Dermatology questions
- Blistering disordersA patient has flaccid blisters that rupture easily and a positive Nikolsky sign. Which c…
- LeprosyIn which type of leprosy is the lepromin test strongly positive?
- Pigmentary disordersA man has well-demarcated chalk-white macules on his hands and around his mouth. A skin…
- Drug reactionsWhich of the following drugs is a well-recognised trigger of Stevens–Johnson syndrome an…