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Dermatology · Papulosquamous disorders: paraphenylenediamine allergy
Sample itemA woman develops severe oedematous dermatitis of the scalp margin, forehead and eyelids 2 days after using a black hair dye at home. Which allergen should be patch tested first?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Paraphenylenediamine
Paraphenylenediamine is the key sensitiser in permanent black hair dyes and temporary black henna. It produces acute facial and scalp dermatitis in a sensitised person. Patch test with PPD is the standard confirmation.
Option by option
A. Paraphenylenediamine (correct)
Correct. Paraphenylenediamine is the classic hair dye allergen.
B. Thiuram mix
Thiuram is a rubber accelerator.
C. Nickel sulphate
Nickel is from jewellery and metal contact.
D. Potassium dichromate
Chromate is from cement and leather.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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