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Dermatology · Papulosquamous disorders: chronic hand eczema
Sample itemA mason with severe chronic hand eczema persisting for over a year fails potent topical steroids and avoidance advice. Which oral drug is specifically indicated for severe chronic hand eczema?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Alitretinoin
Alitretinoin, an oral retinoid, is licensed for severe chronic hand eczema unresponsive to potent topical steroids. It is teratogenic and needs the same pregnancy precautions as other retinoids. Cyclosporine and phototherapy are other options.
Option by option
A. Alitretinoin (correct)
Correct. Alitretinoin is indicated for severe refractory chronic hand eczema.
B. Griseofulvin
Griseofulvin treats dermatophytosis.
C. Itraconazole
Itraconazole is an antifungal.
D. Doxycycline
Doxycycline does not treat hand eczema.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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