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Dermatology · Viral infections: Hutchinson sign in zoster ophthalmicus
Sample itemA 70-year-old has painful vesicles over the left forehead and a vesicle on the tip of the nose. What is the most important management step in addition to oral valacyclovir?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Urgent ophthalmology evaluation
Vesicles at the tip or side of the nose (Hutchinson sign) indicate nasociliary nerve involvement and predict ocular involvement in herpes zoster ophthalmicus. Ocular complications such as keratitis and uveitis can threaten vision, so early ophthalmology assessment is needed. Antivirals should start within 72 hours of rash onset.
Option by option
A. Observation for 2 weeks
Waiting risks vision-threatening complications.
B. Urgent ophthalmology evaluation (correct)
Correct. Hutchinson sign signals ocular risk, so urgent eye review is needed.
C. Topical steroid only
Topical steroids alone do not treat zoster.
D. Dermatology review after the rash heals
Delayed review misses the window for early eye care.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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