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Dermatology · HIV: chronic herpes simplex ulcer
Sample itemA patient has a persistent, enlarging anogenital herpetic ulcer for 6 weeks despite no immunosuppressive drugs. What does this signify?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. An AIDS-defining condition suggesting advanced HIV
Chronic mucocutaneous herpes simplex ulceration lasting more than one month is an AIDS-defining illness, indicating advanced HIV infection. It needs HIV testing, antiviral therapy and ART. Acyclovir resistance should be considered if the ulcer does not heal.
Option by option
A. Primary syphilis
Primary syphilis gives a painless chancre.
B. An AIDS-defining condition suggesting advanced HIV (correct)
Correct. A persistent HSV ulcer over a month is AIDS-defining.
C. Normal healing delay
A 6-week non-healing ulcer is not normal.
D. Contact dermatitis
Contact dermatitis is not ulcerative like this.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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