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Dermatology · Leprosy: silent neuropathy
Sample itemA multibacillary leprosy patient on MDT has gradually developed weakness of finger abduction and reduced sensation in the little finger over 6 weeks, without pain, tenderness or new skin lesions. What is the appropriate step?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Treat as silent neuropathy with oral prednisolone and protect the hand
Silent neuropathy is nerve function impairment without pain or tenderness, and it can progress unnoticed unless nerve function is tested regularly with monofilaments and voluntary muscle testing. It is managed as a reaction-related neuropathy with oral corticosteroids and splinting, while MDT continues. Early treatment improves recovery.
Option by option
A. Reassure, as no pain means no nerve damage
Absence of pain does not exclude nerve damage.
B. Stop MDT and observe
MDT should continue because the bacilli remain a risk.
C. Treat as silent neuropathy with oral prednisolone and protect the hand (correct)
Correct. Silent neuropathy needs steroids and protection while MDT continues.
D. Start thalidomide
Thalidomide is for ENL, not for neuropathy.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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