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Dermatology · Papulosquamous disorders: porokeratosis
Sample itemA skin biopsy from an annular plaque with a thread-like raised keratotic border shows a column of parakeratosis. What is this histological feature called?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Cornoid lamella
The cornoid lamella, a column of parakeratotic cells overlying a hypogranulosis zone, is the histological hallmark of porokeratosis. Lesions are annular plaques with a raised ridge and are mildly premalignant. Munro microabscesses are seen in psoriasis.
Option by option
A. Munro microabscess
Munro microabscesses are in psoriasis.
B. Grenz zone
A Grenz zone is seen in lepromatous leprosy.
C. Civatte body
Civatte bodies are in lichen planus.
D. Cornoid lamella (correct)
Correct. The cornoid lamella marks porokeratosis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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