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Dermatology · Skin tumours: dermoscopic blue-white veil
Sample itemDermoscopy of a pigmented lesion on the back shows an irregular blue-white veil, atypical network and irregular streaks. Which diagnosis is most worrying?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Invasive melanoma
An irregular blue-white veil is a dermoscopic feature of invasive melanoma, representing irregular dense melanin with fibrosis in the dermis. Atypical network, streaks and regression structures add to suspicion. Excisional biopsy is required.
Option by option
A. Cherry angioma
Cherry angioma shows red-purple lacunae.
B. Dermatofibroma
Dermatofibroma shows a central white scar-like patch with peripheral delicate network.
C. Seborrhoeic keratosis
Seborrhoeic keratosis shows milia-like cysts and comedo-like openings.
D. Invasive melanoma (correct)
Correct. Blue-white veil points to invasive melanoma.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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