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Dermatology · Dermatology: transient neonatal pustular melanosis
Sample itemA newborn has pustules present at birth that rupture, leaving collarettes of scale and hyperpigmented macules. Smear shows neutrophils. What is the course?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Benign, with pustules clearing in days and pigmentation fading over weeks to months
Transient neonatal pustular melanosis is a benign neonatal condition, more common in dark skin, with pustules present at birth that evolve into pigmented macules. The smear is neutrophil rich. No treatment is required.
Option by option
A. Benign, with pustules clearing in days and pigmentation fading over weeks to months (correct)
Correct. It is benign and self-resolving.
B. Progresses to epidermolysis bullosa
It does not progress to epidermolysis bullosa.
C. Needs lifelong therapy
No long-term treatment is needed.
D. Requires intravenous acyclovir
Acyclovir is not needed.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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