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Dermatology · Cutaneous markers of malignancy: hypertrichosis lanuginosa acquisita
Sample itemA 58-year-old woman develops sudden growth of fine, soft, unpigmented lanugo-type hair over the face and trunk with weight loss and a smooth red tongue. What should be sought?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Underlying internal malignancy, often of the lung or colon
Hypertrichosis lanuginosa acquisita is a paraneoplastic condition with sudden growth of lanugo hair, often with a smooth tongue, and is associated with malignancies such as lung and colorectal cancers. It requires a search for cancer. The hair may regress with treatment of the tumour.
Option by option
A. Minoxidil use only
Minoxidil use should be excluded, but the picture should prompt a malignancy search.
B. Underlying internal malignancy, often of the lung or colon (correct)
Correct. Acquired lanugo hair growth suggests internal malignancy.
C. Hypothyroidism only
Hypothyroidism does not cause lanugo growth.
D. Polycystic ovary syndrome
PCOS causes terminal-hair hirsutism in younger women.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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