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Dermatology · Dermatology: hyperhidrosis treatment
Sample itemA 22-year-old has severe axillary hyperhidrosis not controlled by 20 percent aluminium chloride hexahydrate. Which next treatment is appropriate?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Intradermal botulinum toxin injections
Primary focal hyperhidrosis is first managed with topical aluminium chloride hexahydrate. If this fails, intradermal botulinum toxin blocks cholinergic sweat gland stimulation for several months, while iontophoresis suits palms and soles. Oral anticholinergics and sympathectomy are later options.
Option by option
A. Topical mupirocin
Mupirocin is an antibiotic.
B. Oral isotretinoin
Isotretinoin is for acne.
C. Intradermal botulinum toxin injections (correct)
Correct. Botulinum toxin is the next step for axillary disease.
D. Oral griseofulvin
Griseofulvin is an antifungal.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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