Gynaecological oncology: sarcoma risk factors: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Gynaecological oncology: sarcoma risk factors

Sample item

Which of the following is a recognised risk factor for uterine sarcoma and carcinosarcoma?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Previous pelvic radiotherapy

Pelvic radiation, tamoxifen use, advanced age and obesity are associated with uterine sarcomas, particularly carcinosarcoma, often appearing many years after exposure. Combined pills protect against endometrial carcinoma, and parity and breastfeeding are protective factors for other gynaecological cancers.

Option by option

  • A. Breastfeeding

    Breastfeeding is protective for ovarian and breast cancer.

  • B. Multiparity

    Multiparity is not a risk factor for sarcoma.

  • C. Combined oral contraceptive use

    Combined pills reduce endometrial cancer risk.

  • D. Previous pelvic radiotherapy (correct)

    Correct. Prior pelvic irradiation increases sarcoma risk.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More OBG questions

Questions about this OBG question

What is the answer to this OBG question?

The best answer is D, Previous pelvic radiotherapy. Pelvic radiation, tamoxifen use, advanced age and obesity are associated with uterine sarcomas, particularly carcinosarcoma, often appearing many years after exposure.

Why is "Breastfeeding" not the answer?

Breastfeeding is protective for ovarian and breast cancer.

Why is "Multiparity" not the answer?

Multiparity is not a risk factor for sarcoma.

Why is "Combined oral contraceptive use" not the answer?

Combined pills reduce endometrial cancer risk.

What concept does this question test?

It tests Gynaecological oncology: sarcoma risk factors in OBG. Combined pills protect against endometrial carcinoma, and parity and breastfeeding are protective factors for other gynaecological cancers.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gynaecological oncology: sarcoma risk factors?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.