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OBG · Gynaecological oncology: radiation fistula
Sample itemA woman 8 months after pelvic radiotherapy for cervical cancer develops continuous urinary leakage, and cystoscopy shows a vesicovaginal fistula with indurated tissue. Biopsy excludes recurrence. What principle guides repair?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Use well-vascularised tissue such as a Martius or omental flap, as irradiated tissue heals poorly
Radiation-induced fistulae occur in ischaemic, fibrotic tissue, so simple closure fails often. Repair is delayed until inflammation settles and recurrence is excluded, and is done with interposition of well-perfused tissue such as a Martius labial fat pad or omentum. Urinary diversion may be needed for complex cases.
Option by option
A. Use well-vascularised tissue such as a Martius or omental flap, as irradiated tissue heals poorly (correct)
Correct. Healthy vascularised tissue interposition improves success.
B. Radiotherapy to the fistula
More radiation would worsen the tissue damage.
C. Repair immediately with simple closure alone
Simple closure in irradiated tissue often breaks down.
D. Treat with long-term catheter drainage and cure is expected
Catheter drainage alone rarely heals radiation fistulae.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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