Gynaecological oncology: colposcopic features: practice question

A OBG question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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OBG · Gynaecological oncology: colposcopic features

Sample item

At colposcopy, which finding most strongly suggests a high-grade cervical lesion?

AFaint translucent acetowhite change at the peripheryBGlycogenated mahogany-brown staining with Schiller iodineCNabothian folliclesDDense acetowhite epithelium with coarse mosaic or punctation and sharp borders

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Dense acetowhite epithelium with coarse mosaic or punctation and sharp borders

Dense, rapidly appearing acetowhite change with sharp margins, coarse punctation, coarse mosaic and atypical vessels indicates high-grade intraepithelial lesion or invasion. Faint, translucent acetowhite areas with fine vessels suggest low-grade lesions. Normal glycogenated epithelium takes up iodine and stains brown.

Option by option

A. Faint translucent acetowhite change at the periphery
Faint acetowhite change suggests low-grade lesions.
B. Glycogenated mahogany-brown staining with Schiller iodine
Mahogany-brown iodine uptake indicates normal epithelium.
C. Nabothian follicles
Nabothian follicles are benign.
D. Dense acetowhite epithelium with coarse mosaic or punctation and sharp borders (correct)
Correct. Dense acetowhite epithelium with coarse vascular patterns suggests high-grade disease.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

Questions about this OBG question

What is the answer to this OBG question?

The best answer is D, Dense acetowhite epithelium with coarse mosaic or punctation and sharp borders. Dense, rapidly appearing acetowhite change with sharp margins, coarse punctation, coarse mosaic and atypical vessels indicates high-grade intraepithelial lesion or invasion.

Why is "Faint translucent acetowhite change at the periphery" not the answer?

Faint acetowhite change suggests low-grade lesions.

Why is "Glycogenated mahogany-brown staining with Schiller iodine" not the answer?

Mahogany-brown iodine uptake indicates normal epithelium.

Why is "Nabothian follicles" not the answer?

Nabothian follicles are benign.

What concept does this question test?

It tests Gynaecological oncology: colposcopic features in OBG. Faint, translucent acetowhite areas with fine vessels suggest low-grade lesions. Normal glycogenated epithelium takes up iodine and stains brown.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Gynaecological oncology: colposcopic features?

Learn management algorithms as steps: PPH, eclampsia, ectopic pregnancy. Then use the flashcards and the other OBG questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.