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Orthopaedics · Bone tumours: hypertrophic osteoarthropathy
Sample itemA 62-year-old smoker has digital clubbing, painful swollen wrists and ankles, and periosteal new bone along the distal tibia and radius on radiographs. Which condition should be suspected?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Hypertrophic osteoarthropathy secondary to bronchogenic carcinoma
Hypertrophic osteoarthropathy is the triad of digital clubbing, periostitis of long bones and arthritis. It is most often secondary to lung cancer and other thoracic disease, and may resolve when the cause is treated. A chest imaging study is the next step.
Option by option
A. Hypertrophic osteoarthropathy secondary to bronchogenic carcinoma (correct)
Correct. Clubbing with periostitis and arthropathy in a smoker suggests lung cancer.
B. Rheumatoid arthritis
Rheumatoid arthritis causes erosions and symmetrical synovitis, not clubbing with periostitis.
C. Osteomyelitis
Osteomyelitis is a localised infection and does not cause symmetrical periostitis with clubbing.
D. Psoriatic arthritis
Psoriatic arthritis causes dactylitis and pencil-in-cup changes.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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