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Pathology · Respiratory: bronchopneumonia
Sample itemA 78-year-old bedridden man after a stroke develops fever and purulent sputum. A chest radiograph shows patchy opacities in both lower zones. At autopsy, what is the characteristic pattern of consolidation?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Patchy foci of neutrophil-rich exudate centred on bronchi and bronchioles
Bronchopneumonia begins in the airways and spreads to adjacent alveoli, producing patchy, often multilobar and bilateral suppurative foci, mostly in dependent lower lobes. It is common at the extremes of age, in debilitated patients and after aspiration. Lobar pneumonia, by contrast, fills a whole lobe homogeneously.
Option by option
A. Patchy foci of neutrophil-rich exudate centred on bronchi and bronchioles (correct)
Correct. Airway-centred patchy suppuration is the defining pattern.
B. Uniform consolidation of an entire lobe with a fibrin-rich exudate
Homogeneous lobar consolidation describes lobar pneumonia, typically from Streptococcus pneumoniae.
C. Interstitial lymphocytic infiltrate with widened alveolar septa and clear alveoli
Interstitial lymphocytic infiltrates describe atypical or viral pneumonia.
D. Hyaline membranes lining alveolar walls with diffuse oedema
Hyaline membranes with diffuse alveolar damage describe ARDS.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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