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Radiology · Nuclear medicine: MUGA scan
Sample itemA woman with breast cancer is to receive trastuzumab and needs a reproducible baseline left ventricular ejection fraction. Which nuclear study provides this?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. Gated blood pool (MUGA) scan with technetium-labelled red cells
A gated equilibrium blood pool study counts the radioactivity in the ventricle across the cardiac cycle and calculates the ejection fraction with little geometric assumption. It is used to monitor cardiotoxic chemotherapy.
Option by option
A. Hepatobiliary scan
A hepatobiliary scan evaluates bile flow.
B. Thyroid uptake scan
A thyroid scan evaluates the thyroid.
C. Gated blood pool (MUGA) scan with technetium-labelled red cells (correct)
Correct. MUGA gives a reproducible ejection fraction.
D. Bone scan with technetium-MDP
A bone scan evaluates the skeleton.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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