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Radiology · Radiotherapy: late effect of neck irradiation
Sample itemA man treated years ago with mantle field radiotherapy for Hodgkin lymphoma should be followed up for which endocrine complication?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Hypothyroidism
The thyroid lies within neck and mantle fields, and radiation damage leads to progressive hypothyroidism years later. Periodic TSH testing is advised after such treatment.
Option by option
A. Diabetes insipidus
Diabetes insipidus is not associated with neck fields.
B. Hyperparathyroidism due to pituitary failure
Hyperparathyroidism is not the characteristic late endocrine effect.
C. Adrenal crisis
Adrenal failure is not expected from this field.
D. Hypothyroidism (correct)
Correct. Hypothyroidism is the commonest late endocrine effect after neck irradiation.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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