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Radiology · Nuclear medicine: captopril renography
Sample itemA young woman has resistant hypertension and a suspected unilateral renal artery stenosis. On captopril renography, what is the characteristic finding in the affected kidney?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. A fall in uptake and delayed excretion after captopril compared with the baseline study
In renal artery stenosis, glomerular filtration depends on angiotensin II constriction of the efferent arteriole. An ACE inhibitor removes that support and the affected kidney's function drops, shown as a worse renogram curve.
Option by option
A. Bilateral symmetrical improvement
Improvement would not occur in the affected side.
B. A fall in uptake and delayed excretion after captopril compared with the baseline study (correct)
Correct. Captopril unmasks the dependence of GFR on angiotensin II.
C. Unchanged curves, which confirms stenosis
Unchanged curves would argue against functionally significant stenosis.
D. Increased glomerular filtration after captopril
GFR falls in the stenosed kidney because efferent tone is lost.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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