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Radiology · Neuroimaging: cerebral cavernous malformation
Sample itemA young adult with seizures has an MRI showing a well-defined lesion with a popcorn appearance of mixed T2 signal and a complete dark haemosiderin rim, and no significant surrounding oedema. Angiography is normal. What is the lesion?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Cavernous malformation
Cavernous malformations are angiographically occult vascular lesions made of blood-filled sinusoids with repeated micro-haemorrhage, so they show a mixed-signal core and a haemosiderin ring that blooms on gradient echo images. Multiple lesions suggest a familial form.
Option by option
A. Abscess
An abscess shows restricted diffusion centrally and an enhancing capsule.
B. Cavernous malformation (correct)
Correct. A popcorn lesion with a haemosiderin rim and normal angiogram is a cavernoma.
C. Arteriovenous malformation
An AVM shows flow voids and a visible nidus on angiography.
D. Glioblastoma
Glioblastoma shows ring enhancement with marked oedema.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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