Papulosquamous: collodion baby: practice question

A Dermatology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Dermatology · Papulosquamous: collodion baby

Sample item

A newborn is covered by a taut, shiny, parchment-like membrane with ectropion and eclabium. What does this presentation commonly evolve into?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. Lamellar ichthyosis or congenital ichthyosiform erythroderma

A collodion membrane at birth is a phenotype of several ichthyoses, most often autosomal recessive congenital ichthyosis such as lamellar ichthyosis (TGM1 mutations). A minority heal to normal skin. Management in the nursery includes humidity, emollients and monitoring for infection and fluid loss.

Option by option

  • A. Normal skin without sequelae in all cases

    Only a minority clear completely, so normal skin is not the rule.

  • B. Epidermolytic ichthyosis only

    Epidermolytic ichthyosis presents with blistering and erythroderma, not a collodion membrane.

  • C. Ichthyosis vulgaris

    Ichthyosis vulgaris does not present at birth.

  • D. Lamellar ichthyosis or congenital ichthyosiform erythroderma (correct)

    Correct. Most collodion babies develop lamellar or congenital ichthyosiform erythroderma.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

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Questions about this Dermatology question

What is the answer to this Dermatology question?

The best answer is D, Lamellar ichthyosis or congenital ichthyosiform erythroderma. A collodion membrane at birth is a phenotype of several ichthyoses, most often autosomal recessive congenital ichthyosis such as lamellar ichthyosis (TGM1 mutations).

Why is "Normal skin without sequelae in all cases" not the answer?

Only a minority clear completely, so normal skin is not the rule.

Why is "Epidermolytic ichthyosis only" not the answer?

Epidermolytic ichthyosis presents with blistering and erythroderma, not a collodion membrane.

Why is "Ichthyosis vulgaris" not the answer?

Ichthyosis vulgaris does not present at birth.

What concept does this question test?

It tests Papulosquamous: collodion baby in Dermatology. A minority heal to normal skin. Management in the nursery includes humidity, emollients and monitoring for infection and fluid loss.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Papulosquamous: collodion baby?

Learn each condition by its primary lesion, site and signature sign. Then use the flashcards and the other Dermatology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.