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Dermatology · Infections: pellagra
Sample itemA man on a maize-based diet with chronic alcohol use has a photosensitive, well-demarcated brown scaly rash around the neck, along with diarrhoea and confusion. What is deficient?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Niacin
Pellagra, caused by niacin (and tryptophan) deficiency, presents with dermatitis, diarrhoea and dementia. The rash on the neck is Casal's necklace. Maize diets and alcoholism are risk factors, and treatment is nicotinamide.
Option by option
A. Niacin (correct)
Correct. Dermatitis, diarrhoea and dementia point to niacin deficiency.
B. Zinc
Zinc deficiency causes acral and periorificial dermatitis, as in acrodermatitis enteropathica.
C. Riboflavin
Riboflavin deficiency gives angular cheilitis and glossitis.
D. Vitamin K
Vitamin K deficiency causes bleeding.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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