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Dermatology · Skin tumours: basal cell carcinoma behaviour
Sample itemA 60-year-old has a pearly papule with rolled edge and telangiectasia on the nose. Which statement about this tumour is correct?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
C. It arises from follicular stem cells and very rarely metastasises
Basal cell carcinoma arises from follicular stem cells in the basal layer and is locally invasive and destructive but very rarely metastatic. It is the most common skin cancer. Surgery, including Mohs surgery for facial high-risk sites, is the usual treatment.
Option by option
A. It frequently metastasises to lymph nodes early
Frequent early nodal spread is not typical of BCC.
B. It arises from melanocytes
Melanoma arises from melanocytes.
C. It arises from follicular stem cells and very rarely metastasises (correct)
Correct. BCC rarely metastasises.
D. It arises from Merkel cells
Merkel cell carcinoma arises from Merkel cell lineage.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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