Try it
Radiology · Radiation safety and radiobiology: shortest latency cancer
Sample itemIn survivors of significant whole-body radiation exposure, which malignancy appears earliest, with a minimum latent period of only a few years?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Leukaemia
Leukaemia has the shortest latent period of radiation-induced cancers, appearing within about 2 to 5 years and peaking in the first decade. Solid tumours usually emerge after 10 years or more. This is why it was the first excess cancer seen in atomic bomb survivors.
Option by option
A. Breast carcinoma
Breast cancer follows after a long latent period.
B. Leukaemia (correct)
Correct. Leukaemia has the shortest latency.
C. Thyroid carcinoma
Thyroid cancer develops over a longer interval.
D. Lung carcinoma
Lung cancer typically appears decades later.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
More Radiology questions
- NeuroimagingWhat is the first investigation of choice in suspected acute subarachnoid haemorrhage?
- Cardiac imagingA 'boot-shaped' heart (coeur en sabot) on a chest radiograph is typical of:
- Musculoskeletal imagingA 'bamboo spine' on a plain radiograph is characteristic of:
- Paediatric radiologyThe 'double bubble' sign on an abdominal radiograph of a newborn suggests: