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Radiology · Neuroimaging: hummingbird sign
Sample itemAn elderly man has frequent backward falls and loss of vertical downgaze. Midline sagittal MRI shows a thin midbrain tegmentum with a relatively preserved pons, resembling a bird with its beak. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Progressive supranuclear palsy
Midbrain atrophy with relative sparing of the pons gives the hummingbird (penguin) sign of progressive supranuclear palsy. Multiple system atrophy shows the hot cross bun sign in the pons. Parkinson disease has no distinctive structural change.
Option by option
A. Parkinson disease
Parkinson disease does not produce marked midbrain atrophy.
B. Progressive supranuclear palsy (correct)
Correct. Midbrain atrophy with a hummingbird profile suggests PSP.
C. Normal pressure hydrocephalus
NPH shows enlarged ventricles with a gait disorder, not midbrain thinning.
D. Multiple system atrophy cerebellar type
MSA-C shows pontine and cerebellar atrophy with a hot cross bun sign.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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