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Radiology · Pancreatic imaging: autoimmune pancreatitis
Sample itemA 55-year-old man has painless obstructive jaundice. CT shows a diffusely enlarged, sausage-shaped pancreas with a hypoattenuating peripheral halo and loss of lobulation. Serum IgG4 is raised. What is the diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Autoimmune (IgG4-related) pancreatitis
Type 1 autoimmune pancreatitis gives a diffusely swollen sausage-like pancreas with a capsule-like rim and responds dramatically to steroids. Adenocarcinoma is a focal mass with upstream duct dilatation. Recognition avoids unnecessary resection.
Option by option
A. Annular pancreas
Annular pancreas causes duodenal obstruction in infancy.
B. Pancreatic adenocarcinoma
Adenocarcinoma is usually focal, not diffuse.
C. Acute necrotising pancreatitis
Necrotising pancreatitis has acute pain and non-enhancing areas.
D. Autoimmune (IgG4-related) pancreatitis (correct)
Correct. The sausage-shaped gland with a rim and raised IgG4 indicates autoimmune pancreatitis.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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