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Radiology · Pancreatic imaging: intraductal papillary mucinous neoplasm
Sample itemAn elderly man has an incidental multilocular pancreatic cystic lesion that communicates with a dilated main pancreatic duct on MRCP, and the ampulla bulges with mucus. What is the likely diagnosis?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Intraductal papillary mucinous neoplasm
IPMN arises from the ductal epithelium, communicates with the duct and may produce mucus that gives a fish-mouth papilla. Main duct involvement carries a higher malignant potential. A pseudocyst follows pancreatitis, and a serous cystadenoma does not communicate.
Option by option
A. Pancreatic pseudocyst
A pseudocyst follows an episode of pancreatitis and has a fibrous wall.
B. Intraductal papillary mucinous neoplasm (correct)
Correct. Duct communication with a patulous ampulla indicates IPMN.
C. Serous cystadenoma
Serous cystadenomas are microcystic with a central scar and do not communicate with the duct.
D. Solid pseudopapillary neoplasm
Solid pseudopapillary neoplasms occur in young women and are solid-cystic masses.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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