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Radiology · Neuroimaging: cerebral fat embolism
Sample itemA young man develops confusion, petechiae and hypoxia two days after a femoral fracture. MRI shows numerous tiny diffusion-restricting foci scattered in the white matter and basal ganglia. What is the likely cause?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Cerebral fat embolism with a starfield pattern
Fat embolism after long bone fracture produces scattered punctate infarcts, giving a starfield pattern on diffusion-weighted images. It is accompanied by respiratory distress and petechiae. Diffuse axonal injury shows haemorrhagic foci on susceptibility imaging after head trauma.
Option by option
A. Hypertensive microbleeds
Hypertensive microbleeds appear on susceptibility imaging, not as restricted diffusion foci.
B. Multiple sclerosis
Multiple sclerosis has periventricular ovoid plaques.
C. Diffuse axonal injury
Diffuse axonal injury follows head trauma and bleeds at the grey-white junction.
D. Cerebral fat embolism with a starfield pattern (correct)
Correct. Starfield DWI foci after a long bone fracture indicate fat embolism.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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