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Radiology · Radiotherapy: planning target volume
Sample itemIn radiotherapy planning, the planning target volume is created by adding a margin to the clinical target volume. What does this margin account for?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
D. Setup error and internal organ motion
The gross tumour volume is the visible tumour and the clinical target volume adds microscopic spread. The planning target volume then adds a margin for patient positioning uncertainty and organ movement, so the CTV receives the prescribed dose.
Option by option
A. The depth of the Bragg peak
The Bragg peak concerns protons and is not what the margin addresses.
B. Tumour hypoxia
Hypoxia is not handled by geometric margins.
C. Microscopic disease beyond the clinical target
Microscopic extension is covered by the CTV.
D. Setup error and internal organ motion (correct)
Correct. The PTV margin covers geometric uncertainty.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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