Nucleotide metabolism: practice question

A Biochemistry question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Biochemistry · Nucleotide metabolism

Sample item

What enzyme synthesizes RNA using a DNA template?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

D. RNA polymerase

The core Nucleotide metabolism principle identifies RNA polymerase as the best answer because it most directly explains the biochemical pathway or tissue response described in the stem.

Option by option

  • A. Topoisomerase

    Topoisomerase does not account for the central finding in this sample.

  • B. Helicase

    Helicase is relevant in another context but is not the best answer here.

  • C. DNA ligase

    DNA ligase does not match the stated nucleotide metabolism mechanism.

  • D. RNA polymerase (correct)

    Correct. RNA polymerase is supported by the key clue given.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Biochemistry questions

Questions about this Biochemistry question

What is the answer to this Biochemistry question?

The best answer is D, RNA polymerase. The core Nucleotide metabolism principle identifies RNA polymerase as the best answer because it most directly explains the biochemical pathway or tissue response described in the stem.

Why is "Topoisomerase" not the answer?

Topoisomerase does not account for the central finding in this sample.

Why is "Helicase" not the answer?

Helicase is relevant in another context but is not the best answer here.

Why is "DNA ligase" not the answer?

DNA ligase does not match the stated nucleotide metabolism mechanism.

What concept does this question test?

It tests Nucleotide metabolism in Biochemistry. The correct option holds because: Correct. RNA polymerase is supported by the key clue given.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Nucleotide metabolism?

Build one table of enzyme deficiency, disease, inheritance and key finding, then revise it by spaced recall. Then use the flashcards and the other Biochemistry questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.