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Biochemistry · Amino acid metabolism
Sample itemWhat amino acid is the precursor of histamine?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
B. Histidine
Histamine is produced by decarboxylation of histidine and acts in allergy, gastric acid secretion, and several neurotransmitter pathways.
Option by option
A. Tryptophan
Tryptophan is a precursor of serotonin and niacin.
B. Histidine (correct)
Correct: histidine is decarboxylated to histamine.
C. Tyrosine
Tyrosine is a precursor of catecholamines and melanin.
D. Methionine
Methionine provides methyl groups through S-adenosylmethionine.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.
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