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Biochemistry · Oxidative phosphorylation
Sample itemWhat molecule directly drives ATP synthase in mitochondria?
Original practice item, not a recalled exam question. Nothing here is recorded.
The answer and the reasoning
A. Proton gradient
Electron transport pumps protons across the inner mitochondrial membrane, and their return down this electrochemical gradient drives ATP synthase.
Option by option
A. Proton gradient (correct)
Correct: proton motive force powers mitochondrial ATP synthase.
B. Glucose
Glucose is metabolized upstream and does not directly turn ATP synthase.
C. Carbon dioxide
Carbon dioxide is a metabolic waste product, not the energy gradient.
D. Sodium gradient
Sodium gradient is not the main mitochondrial ATP synthase driver.
Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.