Hematopathology: practice question

A Pathology question in the style of the NEET PG paper. Answer it first, then read why the right option is right and why each of the others is wrong.

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Pathology · Hematopathology

Sample item

What finding is characteristic of multiple myeloma?

Original practice item, not a recalled exam question. Nothing here is recorded.

The answer and the reasoning

C. Monoclonal plasma-cell proliferation

Multiple myeloma is a plasma-cell neoplasm that produces a monoclonal immunoglobulin and can cause bone lesions, anemia, renal impairment, and infection risk.

Option by option

  • A. Neutrophilic abscess

    Neutrophilic abscess is acute suppurative inflammation.

  • B. Granulomatous inflammation

    Granulomas are organized macrophage collections.

  • C. Monoclonal plasma-cell proliferation (correct)

    Correct: clonal plasma cells define multiple myeloma.

  • D. Microcytic anemia only

    Microcytic anemia alone does not define plasma-cell neoplasia.

Source note: Original NextPrep sample item — pending expert review. This item is original practice material awaiting independent expert review, so confirm important facts in a standard textbook.

More Pathology questions

Questions about this Pathology question

What is the answer to this Pathology question?

The best answer is C, Monoclonal plasma-cell proliferation. Multiple myeloma is a plasma-cell neoplasm that produces a monoclonal immunoglobulin and can cause bone lesions, anemia, renal impairment, and infection risk.

Why is "Neutrophilic abscess" not the answer?

Neutrophilic abscess is acute suppurative inflammation.

Why is "Granulomatous inflammation" not the answer?

Granulomas are organized macrophage collections.

Why is "Microcytic anemia only" not the answer?

Microcytic anemia alone does not define plasma-cell neoplasia.

What concept does this question test?

It tests Hematopathology in Pathology. The correct option holds because: Correct: clonal plasma cells define multiple myeloma.

How hard is this question?

We tag it as an application question: it asks you to use a fact on a patient or a finding. The tag is our own editorial judgement, not an official difficulty rating, so read the reason for every option, not only the answer.

How should I study Hematopathology?

Learn each disease as a bundle: cause, key histology, markers, and the clinical hallmark. Then use the flashcards and the other Pathology questions on this site to test what stuck.

Is this a real NEET PG question?

No. It is an original practice item (editorial status: sample, version 1). NextPrep does not publish recalled or leaked questions, and independent faculty review of this item has not been completed yet, so confirm important facts in a standard textbook.